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New Guidance Available for Review of Developmental Neurotoxicity Studies

EPA and Health Canada have developed new guidance for interpreting developmental neurotoxicity (DNT) data in support of a pesticide registration. This guidance will help scientists in the EPA and Canada’s Pest Management Regulatory Agency (PMRA) evaluate these studies more consistently.

The Developmental Neurotoxicity study assesses behavioral and neurobiological parameters to ascertain the effects of chemicals on the developing animal. The basic purpose of DNT guideline testing is to screen for the potential of chemicals to cause adverse neurodevelopmental outcomes. Continue reading